Analysing twitter data

There is data with tweets about one topic ("vaccine"). One data set has 50 000 000 tweets. It should be analysed possibly with Python or Maxqda or some other tools. In the analysis, I expect such results as for example: who has been tweeting about this topic most of all, time graph etc. This can be done by working with the metadata: information about the users. 

Other ways of analysis, such as sentiment analysis, most frequent topics (words), asociated with this topic in the tweets are also needed, preferrably by using ready soft, such as for example: Word Stat, Maxqda, or other tools.

If you can provide only a part of this analysis, it is also fine. If you are interested to look at the data set, please follow the link: science.curvysoft.se. The person, wsho scraped the data, can give you acccess to the database, if necessary.